pmed.1002647.g001.tif (397.23 kB)
Association between season and cognitive function in adults without cognitive impairment.
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posted on 2018-09-04, 17:27 authored by Andrew S. P. Lim, Chris Gaiteri, Lei Yu, Shahmir Sohail, Walter Swardfager, Shinya Tasaki, Julie A. Schneider, Claire Paquet, Donald T. Stuss, Mario Masellis, Sandra E. Black, Jacques Hugon, Aron S. Buchman, Lisa L. Barnes, David A. Bennett, Philip L. De JagerComposite global cognitive performance as a function of date of assessment, double plotted. Circles indicate means of 2-month bins. Bars indicate standard errors of the mean. Dotted lines indicate fit cosine curve. p-Value indicates significance of contribution of seasonal rhythmicity to overall variance, calculated as described in the text. (A) Baseline measurements for the Religious Orders Study (ROS) and Rush Memory and Aging Project (MAP) cohorts combined (n = 2,234). (B) Baseline measurements for the Minority Aging Research Study (MARS) cohort (n = 527). (C) Baseline measurements for the combined ROS, MAP, and MARS cohorts considered together (n = 2,761).
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EGRSunnybrook Dementia StudyAD pathologyassociationLariboisi ère HospitalROStranscription factorsCNCAlzheimer diseaseReligious Orders Studymemory-clinic-based cohort studiesMinority Aging Research Study4 cognition-associated modulesCI2Cneurobiological correlatesβ 42 levelMEFTHAP 1. LimitationsamplitudeMARSRNASDcerebrospinal fluid AD biomarkersBCL 11A CTCFSDS
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