Assessing the correspondence of pathways implicated by mouse models or the ssNN to human in vivo sepsis.

(A) Comparison of signaling pathways enriched in different strains and mouse models of sepsis and proportion of these pathways enriched in human sepsis. (B) Precision and recall of each mouse model’s predicted human in vivo signaling pathways by strain and type of mouse model. (C) Comparison of signaling pathway predictions by any sepsis mouse model, ssNN, and human in vivo sepsis.