Fig 3.TIF (250.83 kB)
An illustration of how the prior knowledge helping the causal structure construction.
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posted on 2016-04-11, 07:51 authored by Weijia Zhang, Thuc Duy Le, Lin Liu, Zhi-Hua Zhou, Jiuyong LiSolid/dashed black lines indicate the edges correctly/incorrectly detected during the causal structure construction without the prior knowledge; Dotted brown lines indicate the edges added based on prior knowledge.
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miRNA regulation mechanismsIntegrating Gene Regulatory Knowledgeunderstanding cancer mechanismstarget messenger RNAsframeworkperformance increases monotonicallyBRCAmiRNA target predictionmiRNA targetsTranscription FactormiRNA functionsExpression Profiles Motivation microRNAsbreast cancerC ausal m i RNA target D iscoveryEMTmodeling processE xpression profilegene expression dataComputational methodsgene regulation knowledgeTFCIDERsimulation study
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