Amino acid sequence comparison of the mouse, monkey and human ADAM2 proteins.

A. amino acid sequence identities are given as human versus mouse and monkey. B. Comparison of amino acid sequences of mammalian ADAM2. The consensus residues are shaded. Abbreviations: Pro, prodomain; Metallo, metalloprotease domain; Dis, disintegrin domain; Cys, cysteine-rich domain; EGF, epidermal growth factor (EFG)-like domain; T, transmembrane domain; Cy, cytoplasmic tail domain; Ag-1, antigen region of the anti-hADAM2-Cys antibody; and Ag-II, antigen region of the anti-hADAM2-CyT antibody.