Fig 3.TIF (443.46 kB)
ANGPTL8 treatment is well tolerated in mice.
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posted on 2016-07-13, 15:52 authored by Aaron R. Cox, Ornella Barrandon, Erica P. Cai, Jacqueline S. Rios, Julia Chavez, Claire W. Bonnyman, Carol J. Lam, Peng Yi, Douglas A. Melton, Jake A. Kushner(a) Timeline indicating blood glucose sampling, EdU labeling, tail vein injection of MBP or MBP+hBT on day 1 and 2, with sacrifice on day 3. (b-c) Initial (white circles) and final (black circles) (b) body weight (g) and (c) blood glucose (mg/dl). Two-way ANOVA was performed. (d-e) Random fed serum (d) insulin (ng/ml) and (e) triglycerides (mg/dl). Data are mean ± SEM. Buffer, no EdU and buffer, EdU = 4–5 animals per group; MBP and MBP+hBT = 10 animals per group. One-way ANOVA was performed.
