Evidence at the protein level for nesprin-1-beta-1 in spleen and for nesprin-1-alpha-2 in cardiac and skeletal muscle. Nguyen Thuy Duong Glenn E. Morris Le Thanh Lam Qiuping Zhang Caroline A. Sewry Catherine M. Shanahan Ian Holt 10.1371/journal.pone.0094380.g006 https://plos.figshare.com/articles/figure/_Evidence_at_the_protein_level_for_nesprin_1_beta_1_in_spleen_and_for_nesprin_1_alpha_2_in_cardiac_and_skeletal_muscle_/993475 <p>Western blot for nesprin-1 in tissues using antibody against the C-terminal region of nesprin-1 (MANNES1E 8C3). A band the size of nesprin-1-beta-1 (383 kD) was detected in spleen and bands of nesprin-1-alpha-2 (111 kD) were detected in skeletal muscle and heart.</p> 2014-04-09 03:41:15 cell biology Cellular structures and organelles Cell membranes Membrane proteins Transmembrane proteins Molecular cell biology Biochemistry dna DNA amplification proteins Structural proteins rna RNA synthesis Nucleic acids immunology immunochemistry genetics gene expression Gene regulation Genetic dominance Autosomal dominant traits Human genetics Molecular genetics cardiology Cardiovascular diseases cardiomyopathies neurology Muscular dystrophies nesprin-1-beta-1 spleen nesprin-1-alpha-2 cardiac skeletal