10.1371/journal.pone.0093123.g006
Dagmar Fichtner
Dagmar
Fichtner
Bärbel Lorenz
Bärbel
Lorenz
Sinem Engin
Sinem
Engin
Christina Deichmann
Christina
Deichmann
Marieelen Oelkers
Marieelen
Oelkers
Andreas Janshoff
Andreas
Janshoff
Andre Menke
Andre
Menke
Doris Wedlich
Doris
Wedlich
Clemens M. Franz
Clemens M.
Franz
Dynamic force spectroscopy.
Public Library of Science
2014
Biochemistry
proteins
Protein interactions
Recombinant proteins
Biomacromolecule-ligand interactions
chemical biology
cytochemistry
biophysics
biotechnology
Bioengineering
Biological systems engineering
Biomedical Engineering
Biomimetics
biomaterials
Bionanotechnology
cell biology
cell adhesion
cadherins
Cellular structures and organelles
Cell membranes
Membrane proteins
Transmembrane proteins
Molecular cell biology
chemistry
2014-03-27 03:55:26
Figure
https://plos.figshare.com/articles/figure/_Dynamic_force_spectroscopy_/977378
<p>(A) Rupture force distributions obtained at different retraction speeds for the homotypic E1-5 bond rupture. (B) Rupture force <i>F</i><sub>f</sub> as a function of loading rate for homotypic E1-5 (green symbols) or heteromeric E1-2/E1-5 bond rupture (orange symbols). The different symbols represent the maxima identified in the multimodal distribution of rupture force obtained for a given loading rate. For the homotypic E1-5 bond we determined x<sub>u</sub> = 1.1 nm and k<sub>off</sub> = 1.2 × 10<sup>−4</sup> s<sup>−1</sup> (green circles); x<sub>u</sub> = 2.3 nm and k<sub>off</sub> = 1.4 × 10<sup>−5</sup> s<sup>−1</sup> (green triangles). For the heteromeric E1-5/E1-2 bond we determined x<sub>u</sub> = 4.5 nm and k<sub>off</sub> = 5.9 × 10<sup>−7</sup> s<sup>−1</sup> (yellow triangles). The violet stars indicate data taken from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0093123#pone.0093123-Bayas1" target="_blank">[41]</a>.</p>