Generation of IEC-specific Shp2 CKO mice. YamashitaHironori KotaniTakenori ParkJung-ha MurataYoji OkazawaHideki OhnishiHiroshi KuYonson MatozakiTakashi 2014 <p><b>A</b>: Genomic DNA extracted from the indicated organs of adult control (Ctrl) or Shp2 CKO (CKO) mice was subjected to PCR analysis with primers specific for deleted or floxed alleles of <i>Ptpn11</i>. Data are representative of three separate experiments. <b>B</b>: Lysates of IECs (from the ileum or colon) and the indicated organs from control or Shp2 CKO mice were subjected to immunoblot analysis with antibodies to (α-) both Shp2 and β-tubulin (loading control). Data are representative of three (IECs) or two (indicated organs) separate experiments.</p>