10.1371/journal.pone.0221477.g001
Danielle van Keulen
Danielle
van Keulen
Marianne G. Pouwer
Marianne G.
Pouwer
Valur Emilsson
Valur
Emilsson
Ljubica Perisic Matic
Ljubica Perisic
Matic
Elsbet J. Pieterman
Elsbet J.
Pieterman
Ulf Hedin
Ulf
Hedin
Vilmundur Gudnason
Vilmundur
Gudnason
Lori L. Jennings
Lori L.
Jennings
Kim Holmstrøm
Kim
Holmstrøm
Boye Schnack Nielsen
Boye Schnack
Nielsen
Gerard Pasterkamp
Gerard
Pasterkamp
Jan H. N. Lindeman
Jan H. N.
Lindeman
Alain J. van Gool
Alain J.
van Gool
Maarten D. Sollewijn Gelpke
Maarten D. Sollewijn
Gelpke
Hans M. G. Princen
Hans M. G.
Princen
Dennie Tempel
Dennie
Tempel
<i>OSM</i>, <i>OSMR</i> and <i>LIFR</i> mRNA expression is present in human atherosclerotic plaques.
Public Library of Science
2019
AGES
LIFR
Ly -6C High monocytes
artery
Leukemia Inhibitory Factor Receptor
atherosclerosis development
Oncostatin M
APOE
atherosclerotic lesion size
plasma E-selectin levels
results Gene expression analysis
Chronic OSM administration
OSMR
serum OSM levels
post incident CHD survival probability
2019-08-28 17:33:40
Figure
https://plos.figshare.com/articles/figure/_i_OSM_i_i_OSMR_i_and_i_LIFR_i_mRNA_expression_is_present_in_human_atherosclerotic_plaques_/9744134
<p>mRNA expression was measured in normal arteries and in carotid plaques by microarray analysis (A-C) and ISH was used to visualize <i>OSM</i>, <i>OSMR</i> and <i>LIFR</i> mRNA expression (red spots and shown by the black arrows) in two different stages of atherosclerosis development, the late fibroatheroma (D-I) and intimal xanthoma (J-O). A two-sided Student’s t-test assuming non-equal deviation was used to test for significance between normal and atherosclerotic arteries. ***p<0.001, ****p<0.0001.</p>