%0 Figure %A Xia, Wei %A Jiang, Ying %A Li, Yuanyuan %A Wan, Yanjian %A Liu, Juan %A Ma, Yue %A Mao, Zhenxing %A Chang, Huailong %A Li, Gengqi %A Xu, Bing %A Chen, Xi %A Xu, Shunqing %D 2014 %T Effect of BPA on mitochondrial permeability transition (PT) and morphologic features of isolated liver mitochondria. %U https://plos.figshare.com/articles/figure/_Effect_of_BPA_on_mitochondrial_permeability_transition_PT_and_morphologic_features_of_isolated_liver_mitochondria_/948954 %R 10.1371/journal.pone.0090443.g005 %2 https://plos.figshare.com/ndownloader/files/1403906 %K Model organisms %K Animal models %K rat %K Molecular cell biology %K Signal transduction %K Signaling in cellular processes %K Apoptotic signaling %K Cell death %K toxicology %K Toxic agents %K Gastroenterology and hepatology %K Liver diseases %K bpa %K mitochondrial %K permeability %K morphologic %X

(A) Changes of PT in the isolated mitochondria with time. Mitochondria isolated from neonatal rat liver were treated with BPA (0 and 1.47 ng/mL) or BPA-glucuronide (2.60 ng/mL). The decrease in optical density measured at 520 nm with time was normalized to 100. Data are shown of three independent experiments. Ultrastructural features of mitochondria treated with the control (B), BPA-glucuronide (C) and BPA (D). Representative images of transmission electron microscopy were shown (magnification, 10,000×).

%I PLOS ONE