Effect of BPA on mitochondrial permeability transition (PT) and morphologic features of isolated liver mitochondria.
Wei Xia
Ying Jiang
Yuanyuan Li
Yanjian Wan
Juan Liu
Yue Ma
Zhenxing Mao
Huailong Chang
Gengqi Li
Bing Xu
Xi Chen
Shunqing Xu
10.1371/journal.pone.0090443.g005
https://plos.figshare.com/articles/figure/_Effect_of_BPA_on_mitochondrial_permeability_transition_PT_and_morphologic_features_of_isolated_liver_mitochondria_/948954
<p>(A) Changes of PT in the isolated mitochondria with time. Mitochondria isolated from neonatal rat liver were treated with BPA (0 and 1.47 ng/mL) or BPA-glucuronide (2.60 ng/mL). The decrease in optical density measured at 520 nm with time was normalized to 100. Data are shown of three independent experiments. Ultrastructural features of mitochondria treated with the control (B), BPA-glucuronide (C) and BPA (D). Representative images of transmission electron microscopy were shown (magnification, 10,000×).</p>
2014-02-28 03:59:48
Model organisms
Animal models
rat
Molecular cell biology
Signal transduction
Signaling in cellular processes
Apoptotic signaling
Cell death
toxicology
Toxic agents
Gastroenterology and hepatology
Liver diseases
bpa
mitochondrial
permeability
morphologic