Effect of BPA on mitochondrial permeability transition (PT) and morphologic features of isolated liver mitochondria. Wei Xia Ying Jiang Yuanyuan Li Yanjian Wan Juan Liu Yue Ma Zhenxing Mao Huailong Chang Gengqi Li Bing Xu Xi Chen Shunqing Xu 10.1371/journal.pone.0090443.g005 https://plos.figshare.com/articles/figure/_Effect_of_BPA_on_mitochondrial_permeability_transition_PT_and_morphologic_features_of_isolated_liver_mitochondria_/948954 <p>(A) Changes of PT in the isolated mitochondria with time. Mitochondria isolated from neonatal rat liver were treated with BPA (0 and 1.47 ng/mL) or BPA-glucuronide (2.60 ng/mL). The decrease in optical density measured at 520 nm with time was normalized to 100. Data are shown of three independent experiments. Ultrastructural features of mitochondria treated with the control (B), BPA-glucuronide (C) and BPA (D). Representative images of transmission electron microscopy were shown (magnification, 10,000×).</p> 2014-02-28 03:59:48 Model organisms Animal models rat Molecular cell biology Signal transduction Signaling in cellular processes Apoptotic signaling Cell death toxicology Toxic agents Gastroenterology and hepatology Liver diseases bpa mitochondrial permeability morphologic