Perinatal exposure to BPA alters the levels of Cyt c, Bcl-2 and Bax.
Wei Xia
Ying Jiang
Yuanyuan Li
Yanjian Wan
Juan Liu
Yue Ma
Zhenxing Mao
Huailong Chang
Gengqi Li
Bing Xu
Xi Chen
Shunqing Xu
10.1371/journal.pone.0090443.g004
https://plos.figshare.com/articles/figure/_Perinatal_exposure_to_BPA_alters_the_levels_of_Cyt_c_Bcl_2_and_Bax_/948953
<p>(A) Western blot analysis of the Cyt c release from mitochondria into the cytosol in rat livers at 3 and 21 weeks. Western blotting analysis of Bax (B) and Bcl-2 (C) in rat offspring liver at 3, 15 and 21 weeks. The protein expression levels were estimated by densitometry with Gapdh as an internal control. Data are expressed as means ± S.E.M. for three independent experiments (n = 6 rats per group; only 1 offspring was selected per litter).). *<i>P</i><0.05 compared with controls.</p>
2014-02-28 03:59:48
Model organisms
Animal models
rat
Molecular cell biology
Signal transduction
Signaling in cellular processes
Apoptotic signaling
Cell death
toxicology
Toxic agents
Gastroenterology and hepatology
Liver diseases
bpa
alters
cyt
bcl-2