Perinatal exposure to BPA alters the levels of Cyt c, Bcl-2 and Bax. Wei Xia Ying Jiang Yuanyuan Li Yanjian Wan Juan Liu Yue Ma Zhenxing Mao Huailong Chang Gengqi Li Bing Xu Xi Chen Shunqing Xu 10.1371/journal.pone.0090443.g004 https://plos.figshare.com/articles/figure/_Perinatal_exposure_to_BPA_alters_the_levels_of_Cyt_c_Bcl_2_and_Bax_/948953 <p>(A) Western blot analysis of the Cyt c release from mitochondria into the cytosol in rat livers at 3 and 21 weeks. Western blotting analysis of Bax (B) and Bcl-2 (C) in rat offspring liver at 3, 15 and 21 weeks. The protein expression levels were estimated by densitometry with Gapdh as an internal control. Data are expressed as means ± S.E.M. for three independent experiments (n = 6 rats per group; only 1 offspring was selected per litter).). *<i>P</i><0.05 compared with controls.</p> 2014-02-28 03:59:48 Model organisms Animal models rat Molecular cell biology Signal transduction Signaling in cellular processes Apoptotic signaling Cell death toxicology Toxic agents Gastroenterology and hepatology Liver diseases bpa alters cyt bcl-2