%0 Figure %A Pannetier, Delphine %A Reynard, Stéphanie %A Russier, Marion %A Carnec, Xavier %A Baize, Sylvain %D 2014 %T Role of type I IFN in the production of chemokines in MOPV- and LASV-infected iDC/T-cell cocultures. %U https://plos.figshare.com/articles/figure/_Role_of_type_I_IFN_in_the_production_of_chemokines_in_MOPV_and_LASV_infected_iDC_T_cell_cocultures_/898686 %R 10.1371/journal.pntd.0002637.g004 %2 https://plos.figshare.com/ndownloader/files/1344279 %K immunology %K Immune cells %K Antigen-presenting cells %K immunity %K Immunity to infections %K Innate immunity %K Immune response %K microbiology %K Virology %K Animal models of infection %K Emerging viral diseases %K Emerging infectious diseases %K Host-pathogen interaction %K ifn %K chemokines %K mopv- %K lasv-infected %X

(A) The synthesis of mRNAs for CCL4, CCL7, CXCL10 and CXCL11 was evaluated in mock- (gray bars) or MOPV- (black bars) infected iDC cocultured with naïve T cells for 2 days in the presence of neutralizing Ab against CD118. (B) The levels of these mRNAs then were quantified 2 days after restimulation with mock- (gray bars) or inactivated MOPV- (black bars) pulsed iDC of T cells previously cocultured with mock- or MOPV-infected iDC in the presence of irrelevant IgG2a or CD118-neutralizing Ab. Results are expressed as the mean ± SE of 3 independent experiments.

%I PLOS Neglected Tropical Diseases