Tan, Joel W. Y. Murashov, Mikhail D. Rosania, Gus R. Wang, Xueding <i>Ex vivo</i> PA imaging results. <p>CFZ-HCl NP signal normalized to the THb signal for prostates of (A) diluent injected TRAMP mice (DIL-TMP), (B) CFZ-HCl NP injected normal mice (CFZ-NOR), and (C) CFZ-HCl NP injected TRAMP mice (CFZ-TMP). Color bars indicates the CFZ-HCl NP signal normalized to the THb signal as determined by the two-wavelength unmixing. (D) Mean normalized CFZ-HCl NP signal for each group within the organ boundaries as delineated by the US image (shown in the representative images as a white dotted line). * p-value < 0.05, ** p-value < 0.01.</p> transrectal ultrasound scans;clofazimine hydrochloride nanoparticles;prostates Prostate cancer;vivo photoacoustic imaging;photoacoustic contrast agent;prostate cancer progression;prostate-specific antigen tests;prostate cancer;two-wavelength unmixing technique;clofazimine hydrochloride nanoparticle accumulation;FDA-approved antimycobacterial agent;CFZ-HCl NPs 2019-07-15
    https://plos.figshare.com/articles/figure/_i_Ex_vivo_i_PA_imaging_results_/8871881
10.1371/journal.pone.0219655.g005