Tissue-specific magnitude of Sendai virus infection in the respiratory tracts of living mice after direct inoculation and transmission.
Crystal W. Burke
Olga Bridges
Sherri Brown
Richard Rahija
Charles J. Russell
10.1371/journal.ppat.1003786.g008
https://plos.figshare.com/articles/figure/_Tissue_specific_magnitude_of_Sendai_virus_infection_in_the_respiratory_tracts_of_living_mice_after_direct_inoculation_and_transmission_/859956
<p>(<b>A–C</b>) Overall magnitude of infection of primary and challenge infections as determined by integration of daily measurements of total flux with respect to time. The areas under the curve (AUC) of bioluminescence are expressed as the total amount of photons on a log<sub>10</sub> scale. The association between the magnitude of primary and challenge infection (AUC) in the nasopharynx (<b>D</b>), trachea (<b>E</b>), and lungs (<b>F</b>) was determined using linear regression analysis (r<sup>2</sup>) with GraphPad Prism software. Data for airborne transmission corresponds to experiments that had a 7.6-cm separation between donor and recipient mice. No trans. = no transmission, trach. dom. = tracheal dominant infection, rep. diss. = respiratory tract disseminated infection.</p>
2013-11-21 04:38:20
sendai
respiratory
tracts
mice
inoculation