Heme-iron status influences disease severity of NTHI. Blake R. Szelestey Derek R. Heimlich Forrest K. Raffel Sheryl S. Justice Kevin M. Mason 10.1371/journal.ppat.1003709.g007 https://plos.figshare.com/articles/figure/_Heme_iron_status_influences_disease_severity_of_NTHI_/819993 <p>Middle ear pressure was measured by tympanometry (mean ± S.D.) on each day following transbullar introduction of heme-iron replete (black squares) or restricted (gray circles) NTHI (<b>A</b>). Histopathology was assessed by examination of hematoxylin and eosin stained thin sections of naïve (<b>B</b>) or infected middle ear bullae 7 days following introduction of heme-iron replete (<b>C, D</b>) or restricted (<b>E, F</b>) NTHI. Scale bar = 25 µm (<b>B</b>), 50 µm (<b>F</b>), 100 µm (<b>C, D, E</b>). Abbreviations = Bone (B), mucosa (M), biofilm (Bio). Arrows denote capillaries.</p> 2013-10-10 07:53:39 influences severity