Binding of ligands in S1P<sub>1</sub> extracellular pocket.
Shuguang Yuan
Rongliang Wu
Dorota Latek
Bartosz Trzaskowski
Slawomir Filipek
10.1371/journal.pcbi.1003261.g001
https://plos.figshare.com/articles/figure/_Binding_of_ligands_in_S1P_1_extracellular_pocket_/813562
<p>(A) Ligand structures after equilibration: antagonist (yellow) and agonist (purple). Helices represent the crystal structure; (B) The structures of ligand-receptor complexes after 700 ns MD simulations. The antagonist-receptor structure colored in blue, while agonist-receptor structure in yellow.</p>
2013-10-03 01:53:54
ligands
extracellular