Syndecan family is expressed in microvasculature of human lung. Melanie Jannaway Xiaoyuan Yang Jamie E. Meegan Danielle C. Coleman Sarah Y. Yuan 10.1371/journal.pone.0214737.g002 https://plos.figshare.com/articles/figure/Syndecan_family_is_expressed_in_microvasculature_of_human_lung_/8132960 <p>Sections of agarose-inflated human lung were stained for each of the four syndecan ectodomains and the endothelial cell marker, PECAM-1. Confocal images demonstrate co-localization of PECAM-1 with all four syndecan ectodomain proteins, indicating expression throughout the pulmonary microvasculature. Scale bars: 100 μm.</p> 2019-05-15 17:25:17 thrombin receptor PAR 1. barrier integrity disease states barrier function syndecan -3 ectodomain fragments Syndecan proteins plasma protein leakage glycocalyx Rho kinase inhibitor ELISA VE-cadherin-based adherens junction disorganization albumin-bound Evans transmission electron microscopy syndecan subtypes F-actin stress fibers mouse lung intercellular gaps transmigrating cells barrier dysfunction Objective paracellular hyperpermeability thrombotic disease states cleavage products paracellular permeability blot analysis lung microvasculature