10.1371/journal.pone.0214737.g002
Melanie Jannaway
Melanie
Jannaway
Xiaoyuan Yang
Xiaoyuan
Yang
Jamie E. Meegan
Jamie E.
Meegan
Danielle C. Coleman
Danielle C.
Coleman
Sarah Y. Yuan
Sarah
Y. Yuan
Syndecan family is expressed in microvasculature of human lung.
Public Library of Science
2019
thrombin receptor PAR 1.
barrier integrity
disease states
barrier function
syndecan -3 ectodomain fragments
Syndecan proteins
plasma protein leakage
glycocalyx
Rho kinase inhibitor
ELISA
VE-cadherin-based adherens junction disorganization
albumin-bound Evans
transmission electron microscopy
syndecan subtypes
F-actin stress fibers
mouse lung
intercellular gaps
transmigrating cells
barrier dysfunction Objective
paracellular hyperpermeability
thrombotic disease states
cleavage products
paracellular permeability
blot analysis
lung microvasculature
2019-05-15 17:25:17
Figure
https://plos.figshare.com/articles/figure/Syndecan_family_is_expressed_in_microvasculature_of_human_lung_/8132960
<p>Sections of agarose-inflated human lung were stained for each of the four syndecan ectodomains and the endothelial cell marker, PECAM-1. Confocal images demonstrate co-localization of PECAM-1 with all four syndecan ectodomain proteins, indicating expression throughout the pulmonary microvasculature. Scale bars: 100 μm.</p>