10.1371/journal.pone.0074860.t002 Ying Zhou Ying Zhou Yiqin Wang Yiqin Wang Barbara A. Schreader Barbara A. Schreader John R. Nambu John R. Nambu Overexpresion of Morgue deletion (MorgueΔ) mutants exhibit variable viability. Public Library of Science 2013 morgue deletion mutants 2013-09-30 01:56:29 Dataset https://plos.figshare.com/articles/dataset/_Overexpresion_of_Morgue_deletion_Morgue_916_mutants_exhibit_variable_viability_/810854 <p>Effects of widespread expression of Morgue deletion mutants on fly viability. Counts of homozygous non-balancer (+) and heterozygote balancer progeny derived from genetic crosses where P[<i>da</i>-Gal4] was used to drive expression of P[UAS-GFP] or various P[UAS-MorgueΔ] strains. Homozygote (non-balancer) and heterozygote (with either a TM3 or both a CyO and a TM3 balancer) progeny derived from: P[<i>da</i>-Gal4], P[UAS-MorgueΔ]/TM3, P[<i>da</i>-Gal4], P[UAS-GFP]/TM3, or P[UAS-MorgueΔ]/CyO, P[<i>da</i>-Gal4]/TM3 parent flies were counted. Expression of MorgueΔZF, MorgueΔFB, MorgueΔUEV, and MorgueΔZF-FB resulted in reduced Morgue-induced lethality. In contrast, removal of the F box alone retained near complete Morgue-induced lethality. Note that if the homozygotes are fully viable, the expected percentage of viable flies is either 50% or 25% depending on whether one or two balancer chromosomes are present.</p>