De Oliveira, Clara Carolina Silva Pereira, Gabriel Rodrigues Coutinho De Alcantara, Jamile Yvis Santos Antunes, Deborah Caffarena, Ernesto Raul Freire De Mesquita, Joelma Principal component analysis (PCA) of wild-type BDNF and its variant V66M. <p>The plots are showing the first two principal components (PC1 and PC2) extracted from the essential dynamics. The trajectory frames for wild-type BDNF and its variant V66M were colored from blue to red according to time evolution. (A) PCA plot of wild-type BDNF. The first two PCs account for 59.24% of the total structural variance. (B) PCA plot of variant V66M. The first two PCs account for 50.67% of the total structural variance. (C) PCA comparison between wild-type BDNF (black) and its variant V66M (blue).</p> PROCHECK;BDNF;MD analyses;V 66M mutation;BNDF;Verify -3D algorithms;QMEAN;V 66M variant;Phylogenetic analysis;RAMPAGE;precision medicine Brain-derived neurotrophic factor;SIFT;GROMACS 2018.2 package 2019-04-18
    https://plos.figshare.com/articles/figure/Principal_component_analysis_PCA_of_wild-type_BDNF_and_its_variant_V66M_/8013554
10.1371/journal.pone.0215508.g011