10.1371/journal.pone.0073959.g006 Cristina L. Ronchi Cristina L. Ronchi Silviu Sbiera Silviu Sbiera Ellen Leich Ellen Leich Katharina Henzel Katharina Henzel Andreas Rosenwald Andreas Rosenwald Bruno Allolio Bruno Allolio Martin Fassnacht Martin Fassnacht Pathway analysis for genes frequently affected by copy number alterations in both adenomas and carcinomas. Public Library of Science 2013 genes affected alterations adenomas 2013-09-16 01:59:49 Figure https://plos.figshare.com/articles/figure/_Pathway_analysis_for_genes_frequently_affected_by_copy_number_alterations_in_both_adenomas_and_carcinomas_/800146 <div><p>A) List of the most significantly altered pathways according to the GeneGo analysis (Meta Core Analytical suite) including all the genes (n=696 annotated genes) with copy number alterations observed in at least 4 samples (recurrent CNA) in both adenomas and carcinomas. The P values are expresses as logarithmic scale. B) Graphical representation of the Notch signaling pathway map (gene ontology enrichment, <i>P=2.913</i><sup><i>e-4</i></sup>).</p> <p>C) Graphical representation of the WNT5 signaling pathway (gene ontology enrichment, <i>P=3.256</i><sup><i>e-3</i></sup>).</p> <p>Genes with gains are underlined in red and genes with losses in blue. Detailed legend is available at <a href="http://pathwaymaps.com/pdf/MC_legend.pdf" target="_blank"><u>http://pathwaymaps.com/pdf/MC_legend.pdf</u></a>.</p></div>