10.1371/journal.pone.0073959.g005 Cristina L. Ronchi Cristina L. Ronchi Silviu Sbiera Silviu Sbiera Ellen Leich Ellen Leich Katharina Henzel Katharina Henzel Andreas Rosenwald Andreas Rosenwald Bruno Allolio Bruno Allolio Martin Fassnacht Martin Fassnacht Schematic representation of the genetic alterations detected by SNP array analysis in adrenocortical tumors. Public Library of Science 2013 alterations snp adrenocortical 2013-09-16 01:59:49 Figure https://plos.figshare.com/articles/figure/_Schematic_representation_of_the_genetic_alterations_detected_by_SNP_array_analysis_in_adrenocortical_tumors_/800145 <div><p>In the upper panel, the percentage of samples affected by different alterations is reported. Interestingly, the simultaneous presence of numerous LOH and large CNA was observed only in malignant tumors (n=22). In the lower panel, some relevant specific alterations in candidate genes and pathway are reported. In particular, some alterations were observed in all tumors (i.e. isolated small CN gains), while others were found only in carcinomas.</p> <p>CNA=copy number alterations, LOH=loss of heterozygosity) detected by SNP array analysis in adrenocortical adenomas (n=24) and carcinomas (n=22).</p></div>