Primary hHSC expressed NPY receptors are upregulated in NAFLD.
Barbara Sigala
Chad McKee
Junpei Soeda
Valerio Pazienza
Maelle Morgan
Ching-I Lin
Clare Selden
Sara Vander Borght
Gianluigi Mazzoccoli
Tania Roskams
Manlio Vinciguerra
Jude A. Oben
10.1371/journal.pone.0072928.g004
https://plos.figshare.com/articles/figure/_Primary_hHSC_expressed_NPY_receptors_are_upregulated_in_NAFLD_/787246
<p>Semi-quantitative RT-PCR analysis, each lane normalised against its corresponding GAPDH, of liver RNA from patients with NASH fibrosis scored as F0 (n = 3 patients) or F4 (cirrhosis, n = 4 patients) showing human livers with F0 fibrosis having little expression of Y1, Y4 or Y6 NPY but exuberant expression of Y1, Y4 and Y6 NPY in F4 fibrosis (cirrhosis); *p<0.001 compared to F0 control for each receptor subtype, O.D. = optical density.</p>
2013-09-03 02:16:26
hhsc
npy
receptors
upregulated