Primary hHSC expressed NPY receptors are upregulated in NAFLD. Barbara Sigala Chad McKee Junpei Soeda Valerio Pazienza Maelle Morgan Ching-I Lin Clare Selden Sara Vander Borght Gianluigi Mazzoccoli Tania Roskams Manlio Vinciguerra Jude A. Oben 10.1371/journal.pone.0072928.g004 https://plos.figshare.com/articles/figure/_Primary_hHSC_expressed_NPY_receptors_are_upregulated_in_NAFLD_/787246 <p>Semi-quantitative RT-PCR analysis, each lane normalised against its corresponding GAPDH, of liver RNA from patients with NASH fibrosis scored as F0 (n = 3 patients) or F4 (cirrhosis, n = 4 patients) showing human livers with F0 fibrosis having little expression of Y1, Y4 or Y6 NPY but exuberant expression of Y1, Y4 and Y6 NPY in F4 fibrosis (cirrhosis); *p<0.001 compared to F0 control for each receptor subtype, O.D.  =  optical density.</p> 2013-09-03 02:16:26 hhsc npy receptors upregulated