Sun, Ryan Hui, Shirley D. Bader, Gary Lin, Xihong Kraft, Peter Difference between observed and expected number of significant pathways arising from Gene Ontology Biological Process categories. <p>For a given phenotype, expected number is equal to the percentage of all tested pathways belonging to a category multiplied by the total number of significant pathways. The difference between observed and expected counts is expressed as a percentage of the expected number. A value greater than 0 indicates there are more significant pathways in a category than expected. A value less than 0 indicates there are less significant pathways than expected. A number of familiar themes are present, including the high number of significant height pathways related to growth and the high number of significant schizophrenia pathways related to the immune system.</p> GSA;Single Nucleotide Polymorphisms;breast cancer pathway analysis;SNP;Generalized Berk-Jones statistic;set-based testing settings;Genome-Wide Association Studies;GBJ step-down inference technique;FGFR;breast cancer GWAS;gene;summary statistics 2019-03-15
    https://plos.figshare.com/articles/figure/Difference_between_observed_and_expected_number_of_significant_pathways_arising_from_Gene_Ontology_Biological_Process_categories_/7853183
10.1371/journal.pgen.1007530.g006