10.1371/journal.pone.0072676.g008 Javad Noorbakhsh Javad Noorbakhsh Alex H. Lang Alex H. Lang Pankaj Mehta Pankaj Mehta ceRNA Hypothesis. Public Library of Science 2013 Biochemistry Nucleic acids rna RNA interference Computational biology Molecular genetics Gene regulation systems biology genetics gene expression Molecular cell biology biophysics 2013-08-21 02:17:24 Figure https://plos.figshare.com/articles/figure/_ceRNA_Hypothesis_/779353 <p><b>A)</b> Schematic of mRNA crosstalk through a shared pool of microRNAs. stand for transcription rate of each mRNA and correspond to interaction rates between mRNA and microRNA. The other interactions are as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072676#pone-0072676-g001" target="_blank">Figure 1A</a>. <b>B,C)</b> Gillespie results for protein mean (B) and noise (C) as a function of transcription rates of the two mRNAs with equal . Parameters same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072676#pone-0072676-g001" target="_blank">Figure 1</a> with . <b>D,E)</b> Gillespie results for protein mean (D) and noise (E) as a function of transcription rates of the two mRNAs with unequal . Parameters same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072676#pone-0072676-g001" target="_blank">Figure 1</a> with . Noise surface plots have been smoothed and interpolated for better visibillity. <b>F)</b> LNA results for noise of two non-identical species as a function of normalized transcription rates (with ). All the parameters are chosen to be distinct, i.e. .</p>