10.1371/journal.pone.0072676.g008
Javad Noorbakhsh
Javad
Noorbakhsh
Alex H. Lang
Alex
H. Lang
Pankaj Mehta
Pankaj
Mehta
ceRNA Hypothesis.
Public Library of Science
2013
Biochemistry
Nucleic acids
rna
RNA interference
Computational biology
Molecular genetics
Gene regulation
systems biology
genetics
gene expression
Molecular cell biology
biophysics
2013-08-21 02:17:24
Figure
https://plos.figshare.com/articles/figure/_ceRNA_Hypothesis_/779353
<p><b>A)</b> Schematic of mRNA crosstalk through a shared pool of microRNAs. stand for transcription rate of each mRNA and correspond to interaction rates between mRNA and microRNA. The other interactions are as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072676#pone-0072676-g001" target="_blank">Figure 1A</a>. <b>B,C)</b> Gillespie results for protein mean (B) and noise (C) as a function of transcription rates of the two mRNAs with equal . Parameters same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072676#pone-0072676-g001" target="_blank">Figure 1</a> with . <b>D,E)</b> Gillespie results for protein mean (D) and noise (E) as a function of transcription rates of the two mRNAs with unequal . Parameters same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072676#pone-0072676-g001" target="_blank">Figure 1</a> with . Noise surface plots have been smoothed and interpolated for better visibillity. <b>F)</b> LNA results for noise of two non-identical species as a function of normalized transcription rates (with ). All the parameters are chosen to be distinct, i.e. .</p>