10.1371/journal.pone.0072173.g010
Junji Okuda
Junji
Okuda
Shinnichiro Niizuma
Shinnichiro
Niizuma
Tetsuo Shioi
Tetsuo
Shioi
Takao Kato
Takao
Kato
Yasutaka Inuzuka
Yasutaka
Inuzuka
Tsuneaki Kawashima
Tsuneaki
Kawashima
Yodo Tamaki
Yodo
Tamaki
Akira Kawamoto
Akira
Kawamoto
Yohei Tanada
Yohei
Tanada
Yoshitaka Iwanaga
Yoshitaka
Iwanaga
Michiko Narazaki
Michiko
Narazaki
Tetsuya Matsuda
Tetsuya
Matsuda
Souichi Adachi
Souichi
Adachi
Tomoyoshi Soga
Tomoyoshi
Soga
Genzou Takemura
Genzou
Takemura
Hiroshi Kondoh
Hiroshi
Kondoh
Toru Kita
Toru
Kita
Takeshi Kimura
Takeshi
Kimura
The expression of genes related to mitochondrial function under the TAC operation.
Public Library of Science
2013
Biochemistry
enzymes
Enzyme metabolism
metabolism
Carbohydrate metabolism
Model organisms
Animal models
mouse
cardiovascular
Heart failure
Diagnostic medicine
pathology
General pathology
biomarkers
genes
mitochondrial
tac
2013-08-12 02:22:15
Figure
https://plos.figshare.com/articles/figure/_The_expression_of_genes_related_to_mitochondrial_function_under_the_TAC_operation_/769789
<p>The expression of genes related to mitochondrial energy metabolism was decreased in NTg mice with TAC. The genes presented here are (<b>A</b>) transcriptional regulators, (<b>B</b>) fatty acid metabolism, (<b>C</b>) the TCA cycle, and (<b>D</b>) mitochondria. Pgam2 overexpression further decreased the expression of some of these genes, such as ERRα, Tfam, MCAD, Cox5a, and Cox7a1 with TAC. Values are the mean ± SEM. N: NTg mice. P: Pgam2 mice. *p<0.05 versus the same genotype with the sham operation. †p<0.05 versus NTg mice with the same operation. Sham-operated NTg mice: n = 8; sham-operated Pgam2 mice: n = 8; NTg mice with TAC: n = 10; Pgam2 mice with TAC: n = 14.</p>