10.1371/journal.pcbi.1006646.g002
Carmen Lía Murall
Carmen
Lía Murall
Robert Jackson
Robert
Jackson
Ingeborg Zehbe
Ingeborg
Zehbe
Nathalie Boulle
Nathalie
Boulle
Michel Segondy
Michel
Segondy
Samuel Alizon
Samuel
Alizon
Epithelial cell growth in 3D raft cultures.
Public Library of Science
2019
testing hypotheses
ecology-inspired model
pathogen load
bottom-up processes
Human papillomaviruses
epithelial structure
modeling approach
cervicovaginal parameter estimates
infection symptoms
tissue cell cultures
HPV
3 D tissue culture
Epithelial stratification shapes infection dynamics Infections
Chlamydia trachomatis
estimate parameters
infection dynamics
infection strategies
pathogen burden
2019-01-23 18:53:32
Figure
https://plos.figshare.com/articles/figure/Epithelial_cell_growth_in_3D_raft_cultures_/7621640
<p>A) NIKS grown from a single layer over a period of three weeks. Dark pink layer in week 3 consist of cornified cells that accumulate on the surface. B) Immunoflourescence staining: DAPI (blue) is nuclear staining for cell counting and BrdU (pink) is for identifying cells undergoing division; white dots are added to delineate basal lines. C) Data of NIKS growth over time with model fitting. Shading corresponds to 95% prediction interval, assuming the data follows a Poisson distribution.</p>