Histopathological analysis of the skin response to <i>Ph</i>. <i>sergenti</i> salivary proteins.
Elham Gholami
Fabiano Oliveira
Tahereh Taheri
Negar Seyed
Safoora Gharibzadeh
Nasim Gholami
Amir Mizbani
Fatemeh Zali
Sima Habibzadeh
Daniel Omid Bakhadj
Claudio Meneses
Kambiz Kamyab-Hesari
Alireza Sadeghipour
Yasaman Taslimi
Fatemeh khadir
Shaden Kamhawi
Mohammad Ali Mazlomi
Jesus G. Valenzuela
Sima Rafati
10.1371/journal.pntd.0007067.g003
https://plos.figshare.com/articles/figure/Histopathological_analysis_of_the_skin_response_to_i_Ph_i_i_sergenti_i_salivary_proteins_/7579658
<p>Histological evaluation of representative ears of BALB/c mice immunized with <i>PsSP9</i>, <i>PsSP40</i>, <i>PsSP41</i>, <i>PsSP42</i>, <i>PsSP</i>52, <i>Ph</i>. <i>sergenti</i> SGH, empty plasmid, or PBS. Two weeks after the last immunization, mice were challenged in the opposite ear with <i>Ph</i>. <i>sergenti</i> salivary gland homogenate. Ear sections stained with hematoxylin and eosin (H&E staining). Sections were analyzed by optical microscopy under 100× and 400× (A) or 100× (B) magnification and the number of leukocytes enumerated microscopically. Bars represent the mean ±SD. Data are representative of two independent experiments (3–5 mice per group). The <i>p</i> value is indicated for each immunized group compared with the control plasmid group (VR1020).</p>
2019-01-11 18:37:09
sergenti SGH
protein PsSP 9
DTH response
arthropod saliva components
cutaneous leishmaniasis
DNA plasmid coding
PsSP 9
tropica infection
Ph
SP 15 family
IL
vector-borne disease leishmaniasis
CL
BALB
PsSP 9 antibody response
Leishmania tropica Background
IFN -γ expression
saliva-specific antibody response
co-administered Leishmania antigens
months post infection
PpSP 15 family
sergenti saliva