10.1371/journal.pone.0210656.g006 Wen-Yeh Hsieh Wen-Yeh Hsieh Teng-Hsiang Chang Teng-Hsiang Chang Hui-Fang Chang Hui-Fang Chang Wan-Hsuan Chuang Wan-Hsuan Chuang Li-Che Lu Li-Che Lu Chung-Wei Yang Chung-Wei Yang Chih-Sheng Lin Chih-Sheng Lin Chia-Chu Chang Chia-Chu Chang The level of inflammatory signaling pathways in the kidneys of mice with AAI-induced acute nephropathy. Public Library of Science 2019 ACEI angiotensin II formation p-Smad 3 levels BW Ang II level AAI-induced nephropathy progression Ang II levels kidney injury development chymase hydrates Ang Renal chymase-dependent pathway ACE aristolochic acid I-induced CI Ang II nephropathy Angiotensin-converting enzyme C 57BL mice AAI-treated mice role AAI-induced nephropathic mice Renal RAS-related enzyme activities 2019-01-11 18:36:51 Figure https://plos.figshare.com/articles/figure/The_level_of_inflammatory_signaling_pathways_in_the_kidneys_of_mice_with_AAI-induced_acute_nephropathy_/7579643 <p>The expression of p-MEK (<b>A</b>), p-STAT3 (<b>B</b>) and p-Smad3 (<b>C</b>) in kidney tissues was determined using Western blotting and representative results of Western blotting are shown (<b>D</b>). All values are expressed as the means ± SD from each group (n = 9). * and ** indicate <i>p</i> < 0.05 and <i>p</i> < 0.01 compared to the Control group, respectively; †† indicates <i>p</i> < 0.01 compared to the AAI group.</p>