Changes in RAS enzyme activity in kidneys of mice with AAI-induced acute nephropathy. Wen-Yeh Hsieh Teng-Hsiang Chang Hui-Fang Chang Wan-Hsuan Chuang Li-Che Lu Chung-Wei Yang Chih-Sheng Lin Chia-Chu Chang 10.1371/journal.pone.0210656.g004 https://plos.figshare.com/articles/figure/Changes_in_RAS_enzyme_activity_in_kidneys_of_mice_with_AAI-induced_acute_nephropathy_/7579637 <p>Renal ACE (<b>A</b>), chymase (<b>B</b>) and ACE2 (<b>C</b>) activities were determined, and the related activity levels are shown as levels relative to the Control group. All values are expressed as the means ± SD from each group (n = 9). * and ** indicate <i>p</i> < 0.05 and <i>p</i> < 0.01 compared to the Control group, respectively; †† indicates <i>p</i> < 0.01 compared to the AAI group.</p> 2019-01-11 18:36:51 ACEI angiotensin II formation p-Smad 3 levels BW Ang II level AAI-induced nephropathy progression Ang II levels kidney injury development chymase hydrates Ang Renal chymase-dependent pathway ACE aristolochic acid I-induced CI Ang II nephropathy Angiotensin-converting enzyme C 57BL mice AAI-treated mice role AAI-induced nephropathic mice Renal RAS-related enzyme activities