Changes in RAS enzyme activity in kidneys of mice with AAI-induced acute nephropathy.
Wen-Yeh Hsieh
Teng-Hsiang Chang
Hui-Fang Chang
Wan-Hsuan Chuang
Li-Che Lu
Chung-Wei Yang
Chih-Sheng Lin
Chia-Chu Chang
10.1371/journal.pone.0210656.g004
https://plos.figshare.com/articles/figure/Changes_in_RAS_enzyme_activity_in_kidneys_of_mice_with_AAI-induced_acute_nephropathy_/7579637
<p>Renal ACE (<b>A</b>), chymase (<b>B</b>) and ACE2 (<b>C</b>) activities were determined, and the related activity levels are shown as levels relative to the Control group. All values are expressed as the means ± SD from each group (n = 9). * and ** indicate <i>p</i> < 0.05 and <i>p</i> < 0.01 compared to the Control group, respectively; †† indicates <i>p</i> < 0.01 compared to the AAI group.</p>
2019-01-11 18:36:51
ACEI
angiotensin II formation
p-Smad 3 levels
BW
Ang II level
AAI-induced nephropathy progression
Ang II levels
kidney injury development
chymase hydrates Ang
Renal chymase-dependent pathway
ACE
aristolochic acid I-induced
CI
Ang II
nephropathy Angiotensin-converting enzyme
C 57BL mice
AAI-treated mice
role
AAI-induced nephropathic mice
Renal RAS-related enzyme activities