10.1371/journal.ppat.1007515.g003
John V. Dzimianski
John V.
Dzimianski
Brianna S. Beldon
Brianna S.
Beldon
Courtney M. Daczkowski
Courtney M.
Daczkowski
Octavia Y. Goodwin
Octavia
Y. Goodwin
Florine E. M. Scholte
Florine
E. M. Scholte
Éric Bergeron
Éric
Bergeron
Scott D. Pegan
Scott D.
Pegan
vOTU preferences for different di-Ub linkages.
Public Library of Science
2019
novel X-ray crystal structures
Crimean-Congo hemorrhagic fever virus
Recent genomic characterization
ISG 15 fluorogenic substrates
Hughes orthonairovirus species
Nairoviridae family
vOTU substrate preferences
DUB
deubiquitinase activity Post-translational modification
gene product 15
nairovirus genomic diversity
tumor domain protease
2019-01-10 19:09:59
Figure
https://plos.figshare.com/articles/figure/vOTU_preferences_for_different_di-Ub_linkages_/7575221
<p>(A) Activity towards K48, K63, and K11 linked di-Ub FRET-TAMRA substrates. Values shown are the mean ± standard deviation of two independent experiments. (B) Gel cleavage assay of unlabeled di-Ub, visualized by Commassie Blue staining. (C) Summary of currently investigated vOTU di-Ub activity (present study and [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1007515#ppat.1007515.ref032" target="_blank">32</a>]).</p>