Delineation of four categories of translation problems, those of generalizing insights from model systems to human <i>in vivo</i> contexts. BrubakerDouglas K. ProctorElizabeth A. M. HaigisKevin LauffenburgerDouglas A. 2019 <p>The coverage and resolution of the available data determines the category. Categories one through three are potentially approachable by data integration of model system and human datasets and semi-supervised learning approaches.</p>