MiR-196b expression and CpG island methylation. Yue Liu Wenling Zheng Yanbin Song Wenli Ma Hong Yin 10.1371/journal.pone.0068442.g001 https://plos.figshare.com/articles/figure/_MiR_196b_expression_and_CpG_island_methylation_/748988 <p>(A) MiR-196b expression levels were significantly lower in CML patients than in healthy controls. (B) Predicted miR-196b promoter CpG islands, obtained from CpG Island Searcher software. (C) The BSP detection method demonstrated decreased methylation after treatment. (D) MSP test results for 45 patients with leukemia and 10 healthy controls. N represents the healthy controls.</p> 2013-07-19 01:45:05 genetics Molecular genetics Gene regulation epigenetics Molecular cell biology gene expression DNA modification RNA interference Nucleic acids rna Signal transduction Signaling in selected disciplines Oncogenic signaling hematology Hematologic cancers and related disorders leukemias Chronic myeloid leukemia cpg