Chi, Lijun Galtseva, Alevtina Chen, Lin Mo, Rong Hui, Chi-chung D. Rosenblum, Norman Model of <i>Kif3a-</i>mediated regulation of nephron number. <p>A <i>Kif3a</i> control is required in both ureteric and metanephric mesenchyme cells for processes that control nephron number. In ureteric cells <i>Kif3a</i> acts in a GLI3R-dependent manner to control expression of <i>Wnt11/Ret</i> and ureteric branching. In metanephric mesenchyme cells, <i>Kif3a</i> functions to control cell survival and expression of <i>Fgf8</i>, which is required for maturation of nephrogenic progenitors. The lineage-specific functions of <i>Kif3a</i> in ureteric and metanephric mesenchyme cells converge to control nephron number.</p> developmental biology;Molecular development;morphogens;signaling;morphogenesis;Birth defects;Growth control;embryology;Model organisms;Animal models;mouse;Nephrology;Developmental nephrology;nephron 2013-06-07
    https://plos.figshare.com/articles/figure/_Model_of_Kif3a_mediated_regulation_of_nephron_number_/714623
10.1371/journal.pone.0065448.g008