Simulated dataset.
Flora Alarcon
Violaine Planté-Bordeneuve
Malin Olsson
Grégory Nuel
10.1371/journal.pone.0203860.g001
https://plos.figshare.com/articles/figure/Simulated_dataset_/7129160
<p>Reference and estimation of the survival function <i>S</i>(<i>t</i>) for carriers with 95% point-wise confidence intervals (dashed lines). A total of <i>n</i> = 3,285 (1,641 males and 1,644 females) individuals including 441 affected and 319 genotyped. Left: simulation and estimation without gender effect. Right: simulation and estimation with a proportional protective effect for females (gender = 2).</p>
2018-09-25 17:31:26
EM
survival function
Weibull survival
Bayesian networks
family samples
hazard model
factors effects
prevention strategies
survival procedures
pedigrees data
mutation carriers
Kaplan-Meier non-parametric estimates
mutation carriers management
mutation carrier survival estimates
survival function estimation
risk assessment
Non-parametric estimation