10.1371/journal.pcbi.1006358.g002
Silke Bergeler
Silke
Bergeler
Erwin Frey
Erwin
Frey
Exploring the parameter space.
Public Library of Science
2018
bacterium Myxococcus xanthus
daughter cells
Pom cluster oscillates
PomY form
PomZ fluxes
Pom cluster dynamics
cluster dynamics change
cargo localization
attachment rates
oscillatory cluster movements
friction coefficient
PomZ proteins
PomZ dimer
diffusive PomZ fluxes
cell division
Pom cluster
cell division site
Myxococcus xanthus
parameter range
ATP hydrolysis rate
ParAB S systems
proteins PomX
semi-analytical approach
midnucleoid localization
PomZ dimers
2018-08-13 17:24:35
Figure
https://plos.figshare.com/articles/figure/Exploring_the_parameter_space_/6961118
<p>(A-F) Stochastic simulations show different qualitative behavior of the PomXY cluster trajectories when the model parameters are altered. We performed stochastic simulations using the parameter set given in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006358#pcbi.1006358.s005" target="_blank">S1 Table</a>, with one of the parameters varied as indicated. In D, the diffusion constants of PomZ on the nucleoid and on the PomXY cluster are set to the same value. The result for the parameter set given in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006358#pcbi.1006358.s005" target="_blank">S1 Table</a> is always shown in black for comparison purposes. The average cluster trajectories are shown as unbroken or dashed lines and the shaded regions indicate the region of ± one standard deviation. In the simulations, the initial position of the PomXY cluster is chosen such that the left edge of the cluster coincides with the left edge of the nucleoid (for more details see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006358#sec012" target="_blank">Materials and methods</a> section). For the calculation of the mean and standard deviations the cluster positions are grouped into time intervals of 3.33 min. For each parameter set we simulated at least 100 trajectories.</p>