%0 Figure %A Aarts, Suzanne A. B. M. %A Reiche, Myrthe E. %A Toom, Myrthe den %A Beckers, Linda %A J. J. Gijbels, Marion %A Gerdes, Norbert %A P. J. de Winther, Menno %A Lutgens, Esther %D 2018 %T Lipid accumulation was not affected by deficiency of macrophage CD40. %U https://plos.figshare.com/articles/figure/Lipid_accumulation_was_not_affected_by_deficiency_of_macrophage_CD40_/6956876 %R 10.1371/journal.pone.0202150.g005 %2 https://plos.figshare.com/ndownloader/files/12756797 %K adipose tissue leukocyte infiltration %K WT %K 40L %K Macrophage CD 40 %K SFD %K adipose tissue inflammation %K 40-CD %K ameliorates adipose tissue inflammation %K insulin resistance %K HFD %K CD 40 flfl LysM cre %K increases insulin sensitivity %K macrophage CD 40 %K adipose tissue weight %K DIO %K plasma adiponectin levels %K triglyceride levels %K macrophage CD 40. CD 40 flfl LysM cre mice %K adipose tissue cytokine levels %X

(A) Liver weight (n = 16 for HFD and n = 7 for SFD) (B) Quantification of oil-red-o stained area in the liver (n = 16 for HFD and n = 7 for SFD). (C) Liver TG levels (n = 6-9/group). (D) Liver total cholesterol levels (n = 6-9/group). (E) Representative pictures of ORO staining of the livers. (F) Histopathological score of liver steatosis (n = 16/group). (G). Plasma ALT levels (n = 7-9/group). (H). Plasma AST levels (n = 7-9/group). (I) mRNA expression of liver lipid metabolism genes (n = 7-10/group). Data is presented as mean ± SEM. N.D. means ‘not detectable’.

%I PLOS ONE