Lipid accumulation was not affected by deficiency of macrophage CD40. Suzanne A. B. M. Aarts Myrthe E. Reiche Myrthe den Toom Linda Beckers Marion J. J. Gijbels Norbert Gerdes Menno P. J. de Winther Esther Lutgens 10.1371/journal.pone.0202150.g005 https://plos.figshare.com/articles/figure/Lipid_accumulation_was_not_affected_by_deficiency_of_macrophage_CD40_/6956876 <p><b>(A)</b> Liver weight (n = 16 for HFD and n = 7 for SFD) <b>(B)</b> Quantification of oil-red-o stained area in the liver (n = 16 for HFD and n = 7 for SFD). <b>(C)</b> Liver TG levels (n = 6-9/group). <b>(D)</b> Liver total cholesterol levels (n = 6-9/group). <b>(E)</b> Representative pictures of ORO staining of the livers. <b>(F)</b> Histopathological score of liver steatosis (n = 16/group). <b>(G)</b>. Plasma ALT levels (n = 7-9/group). <b>(H)</b>. Plasma AST levels (n = 7-9/group). <b>(I)</b> mRNA expression of liver lipid metabolism genes (n = 7-10/group). Data is presented as mean ± SEM. N.D. means ‘not detectable’.</p> 2018-08-10 17:39:43 adipose tissue leukocyte infiltration WT 40L Macrophage CD 40 SFD adipose tissue inflammation 40-CD ameliorates adipose tissue inflammation insulin resistance HFD CD 40 flfl LysM cre increases insulin sensitivity macrophage CD 40 adipose tissue weight DIO plasma adiponectin levels triglyceride levels macrophage CD 40. CD 40 flfl LysM cre mice adipose tissue cytokine levels