%0 Figure %A Aarts, Suzanne A. B. M. %A Reiche, Myrthe E. %A Toom, Myrthe den %A Beckers, Linda %A J. J. Gijbels, Marion %A Gerdes, Norbert %A P. J. de Winther, Menno %A Lutgens, Esther %D 2018 %T Adipose tissue inflammation is slightly increased in macrophage CD40 deficient mice without resulting in altered cytokine release. %U https://plos.figshare.com/articles/figure/Adipose_tissue_inflammation_is_slightly_increased_in_macrophage_CD40_deficient_mice_without_resulting_in_altered_cytokine_release_/6956870 %R 10.1371/journal.pone.0202150.g004 %2 https://plos.figshare.com/ndownloader/files/12756791 %K adipose tissue leukocyte infiltration %K WT %K 40L %K Macrophage CD 40 %K SFD %K adipose tissue inflammation %K 40-CD %K ameliorates adipose tissue inflammation %K insulin resistance %K HFD %K CD 40 flfl LysM cre %K increases insulin sensitivity %K macrophage CD 40 %K adipose tissue weight %K DIO %K plasma adiponectin levels %K triglyceride levels %K macrophage CD 40. CD 40 flfl LysM cre mice %K adipose tissue cytokine levels %X

(A) Quantification of CD45 staining for leukocytes of EpAT (n = 16 for HFD and n = 7 for SFD). (B) Quantification of Mac3 staining for macrophages in EpAT (n = 16 for HFD and n = 7 for SFD). (C) Quantification of CD3+ staining for T cells in EpAT (n = 16 for HFD and n = 7 for SFD). (D) Flow cytometric analysis of leukocyte subsets in EpAT, as % of total CD45+ leukocytes (n = 7-9/group). (E) mRNA expression of inflammatory markers in EpAT (n = 7-9/group). Data is presented as mean ± SEM.

%I PLOS ONE