Characteristics of studies included in review, first CD4 cell count measurement after HIV diagnosis and mortality rates prior to initiation of antiretroviral therapy (ART). Catrina Mugglin Gilles Wandeler Janne Estill Matthias Egger Nicole Bender Mary-Ann Davies Olivia Keiser 10.1371/journal.pone.0056446.t001 https://plos.figshare.com/articles/dataset/_Characteristics_of_studies_included_in_review_first_CD4_cell_count_measurement_after_HIV_diagnosis_and_mortality_rates_prior_to_initiation_of_antiretroviral_therapy_ART_/665351 <p>n.r. not reported.</p>*<p>Immunological and clinical eligibility criteria for ART initiation were the following:</p><p></p><p></p><p>WHO 2003 guidelines <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0056446#pone.0056446-World4" target="_blank">[33]</a>: all children if WHO paediatric stage III.</p><p>WHO paediatric stage I (only when CD4 count available) or paediatric stage II:</p><p><18 months: CD4 percentage <20%.</p><p>≥18 months: CD4 percentage <15%.</p><p></p><p></p><p>WHO 2006 guidelines <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0056446#pone.0056446-World2" target="_blank">[20]</a>: all children if WHO stage 3 or 4 (there are specific rules for WHO stage 3 in case of co-infections).</p><p>WHO stage 1 or 2 (total lymphocyte counts are used in sites where CD4 values cannot be determined):</p><p><1 year: CD4 percentage <25% or absolute CD4 cell count <1500 cells/µl.</p><p>1 to <3 years: CD4 percentage <20% or absolute CD4 cell count <750 cells/µl.</p><p>3 to <5 years: CD4 percentage <15% or absolute CD4 cell count <350 cells/µl.</p><p>≥5 years: CD4 percentage <15% or absolute CD4 cell count <200 cells/µl.</p><p></p><p></p><p>• WHO 2010 guidelines <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0056446#pone.0056446-World3" target="_blank">[21]</a>: all children if <2 years or in WHO stage 3 or 4.</p><p>WHO stage 1 or 2:</p><p>2 to <5 years: CD4 percentage ≤25% or absolute CD4 cell count ≤750 cells/µl.</p><p>≥5 years: ≤350 cells/µl.</p><p></p><p></p><p></p><p>WHO 2003 guidelines <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0056446#pone.0056446-World4" target="_blank">[33]</a>: all children if WHO paediatric stage III.</p><p>WHO paediatric stage I (only when CD4 count available) or paediatric stage II:</p><p><18 months: CD4 percentage <20%.</p><p>≥18 months: CD4 percentage <15%.</p><p>WHO 2006 guidelines <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0056446#pone.0056446-World2" target="_blank">[20]</a>: all children if WHO stage 3 or 4 (there are specific rules for WHO stage 3 in case of co-infections).</p><p>WHO stage 1 or 2 (total lymphocyte counts are used in sites where CD4 values cannot be determined):</p><p><1 year: CD4 percentage <25% or absolute CD4 cell count <1500 cells/µl.</p><p>1 to <3 years: CD4 percentage <20% or absolute CD4 cell count <750 cells/µl.</p><p>3 to <5 years: CD4 percentage <15% or absolute CD4 cell count <350 cells/µl.</p><p>≥5 years: CD4 percentage <15% or absolute CD4 cell count <200 cells/µl.</p><p>• WHO 2010 guidelines <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0056446#pone.0056446-World3" target="_blank">[21]</a>: all children if <2 years or in WHO stage 3 or 4.</p><p>WHO stage 1 or 2:</p><p>2 to <5 years: CD4 percentage ≤25% or absolute CD4 cell count ≤750 cells/µl.</p><p>≥5 years: ≤350 cells/µl.</p>**<p>Absolute CD4 count A, percentage CD4 P.</p>***<p>Of 162 HIV exposed children, all 24 children who were diagnosed HIV positive were included.</p> 2013-02-20 01:29:11 studies included cd4 hiv rates initiation antiretroviral