%0 Figure %A M. Griffing, Sean %A M. Rachid Viana, Giselle %A Mixson-Hayden, Tonya %A Sridaran, Sankar %A Alam, Mohammad Tauqeer %A de Oliveira, Alexandre Macedo %A W. Barnwell, John %A A. Escalante, Ananias %A Marins Povoa, Marinete %A Udhayakumar, Venkatachalam %D 2013 %T dhfr triple mutant He changes over time (50R/51I/108N). %U https://plos.figshare.com/articles/figure/_dhfr_triple_mutant_H_e_changes_over_time_50R_51I_108N_/653555 %R 10.1371/journal.pone.0058984.g005 %2 https://plos.figshare.com/ndownloader/files/989240 %K triple %K mutant %X

The figure shows variation in He surrounding dhfr for parasites carrying a 50R/51I/108N mutants during the 1980s (nā€Š=ā€Š14) and 1990s (nā€Š=ā€Š92). Note that He around the triple mutants seems similar between the two decades. The two flat, dashed lines represent two different estimates of neutral He in Brazil.

%I PLOS ONE