10.1371/journal.pone.0058857.g006
Aseervatham Anusha Amali
Aseervatham
Anusha Amali
Lawrence Sie
Lawrence
Sie
Christoph Winkler
Christoph
Winkler
Mark Featherstone
Mark
Featherstone
<i>hoxd4a</i> is required for hemangioblast formation.
Public Library of Science
2013
findings place hoxd 4a
cdx
Hox genes
ventral-most mesoderm fated
hoxd 4a function
group paralog Hoxd 4 display malformations
13 hours post fertilization
meis 1.1 expression
hemangioblast markers scl 1
hoxd 4a acts
PLM
orthologous hoxd 4a gene
Zebrafish hoxd 4a Acts Upstream
meis 1.1
2013-03-16 07:35:55
Figure
https://plos.figshare.com/articles/figure/_hoxd4a_is_required_for_hemangioblast_formation_/653060
<p>(A,B) Normal expression at 13 hpf of posterior hemangioblast markers <i>scl1</i> (A) and <i>lmo2</i> (B) in the PLM. (C,D) Expression of these markers is greatly reduced in <i>hoxd4a</i> morphants, but is rescued by co-injection of capped mRNA for <i>hoxd4a</i> (E,F). Ratios indicate the fraction of embryos showing the presented phenotype. Anterior is to the left. A, C and E are dorsal views of flat-mounted specimens while B, D and F are lateral views. Scale bars equal 100 µm. A is at a lower magnification than C and E.</p>