Illustration of the relative zones of inhibition of screened compounds versus MU1140 and OG253. Johan A. Kers Anthony W. DeFusco Jae H. Park Jin Xu Mark E. Pulse William J. Weiss Martin Handfield 10.1371/journal.pone.0197467.g003 https://plos.figshare.com/articles/figure/Illustration_of_the_relative_zones_of_inhibition_of_screened_compounds_versus_MU1140_and_OG253_/6494795 <p>Controls are boxed in the upper-left corner and include blanks (Column 1, negative control), MU1140 (Column 2, positive control) and OG253 (Column 3, comparator).</p> 2018-06-12 18:01:08 substitution variants performer OG 716 lantibiotic Mutacin 1140 fit-for-purpose lantibiotic vivo testing novel antibiotics novel lantibiotic infections Lantibiotics MU 1140-derived variants novel mechanism CDI hamster model CDAD 3 weeks post infection biologically-relevant systems