Molparia, Bhuvan Oliveira, Glenn Wagner, Jennifer L. G. Spencer, Emily Torkamani, Ali Cell free DNA CNV detection. <p>A) Distribution of normalized 10Kb bin values in cfDNA in each cancer and normal blood sample. B) Heatmap of the genome broken down in large chromosomal segments colored based on their median normalized bin value. A value of 1 represents a normal diploid segment, values less than one are potential deletions, and values higher than one are potential amplifications. C) Distribution of the number of potential CNVs detected in normal vs colorectal cancer cfDNA samples.</p> CNV detection;parent tissue samples;cancer progression;sample size;cfDNA sequencing;copy numbers variations;stage colorectal cancer;pilot stage study;24 CRC samples;scale exploration;confidence interval;DNA sequencing;point mutations;CNV detection Circulating tumor DNA;feasibility study;tumor DNA;colorectal cancer diagnosis;sequencing costs;sub-clonal nature;ctDNA signal 2018-05-23
    https://plos.figshare.com/articles/figure/Cell_free_DNA_CNV_detection_/6329873
10.1371/journal.pone.0196826.g001