%0 Figure %A Liang, Dongchun %A Woo, Jeong-Im %A Shao, Hui %A K. Born, Willi %A L. O'Brien, Rebecca %A J. Kaplan, Henry %A Sun, Deming %D 2018 %T The formalin-fixed γδ T cells were as effective as live γδ T cells in inhibition of Foxp3 T cell response. %U https://plos.figshare.com/articles/figure/The_formalin-fixed_T_cells_were_as_effective_as_live_T_cells_in_inhibition_of_Foxp3_T_cell_response_/6283619 %R 10.1371/journal.pone.0197189.g007 %2 https://plos.figshare.com/ndownloader/files/11495579 %K γδ T cell cultures %K Non-activated γδ T cells %K Foxp 3 T cell interactions %K adenosine receptors %K Extracellular adenosine metabolism %K Activated γδ T cells %K Foxp 3 T cell expansion %K γδ T cells %K γδ T cell-targeted immunotherapies %K Foxp 3 T cell response %K 2AR %X

In a 24-well plate, αβ responder T cells (1 x 106/well] isolated from immunized TCR-δ-/- mice were cultured in IL-2-containing medium (1 ng/ml) for 5 days with (7B-7D) or without (7A) addition of γδ T cells–either alive (7B) or formalin-fixed (7C&D) and in the absence (Fig 7A–7C) or presence (Fig 7D) of an A2AR antagonist (SCH58261, 100nM). Results shown are from a single experiment and are representative of three experiments.

%I PLOS ONE