Paiatto, Lisiery N. Silva, Fernanda G. D. Yamada, Áureo T. M. S. C. Tamashiro, Wirla Simioni, Patricia U. Adoptive transfer of CD11c<sup>+</sup> dendritic cells isolated from OVA-tolerant mice reduces severity of experimental colitis. <p>(Panel A) Characterization of DCs isolated from spleens of naive and OVA treated mice (nDC and tDC, respectively): The frequency of the CD40<sup>+</sup>, CD80<sup>+</sup>, and CD86<sup>+</sup>CD11c<sup>+</sup> MHCII<sup>+</sup> cells in DC preparations and the fluorescence intensity (MFI) geometric means of these markers were assessed by flow cytometry. (Panel B) Temporal changes in body weight: body weight was taken on a daily basis from 1 to 5 days after TNBS instillation and is represented as mean percentage in relation to the mean initial value (100%). (Panel C) Clinical signs: Clinical signs of colitis were evaluated for the presence of diarrhea, rectal prolapse, bleeding, and cachexia, assigning a score ranging from 0 to 2, with 0: no change, 1: slight change, and 2: severe change. Data are expressed as mean and S.E.M. (n = 5) and are representative of three independent experiments. ANOVA followed by Bonferroni post-test were used to determine statistical significance (p <0.05).</p> splenic cell cultures;TNBS;Adoptive transfer;CD 11c;OVA;coliti;IFN;MHC;BALB;intrarectal instillation;DC;CD 11;T cell responses;II;IL;MHCII;dendritic cells;spleen cells 2018-05-08
    https://plos.figshare.com/articles/figure/Adoptive_transfer_of_CD11c_sup_sup_dendritic_cells_isolated_from_OVA-tolerant_mice_reduces_severity_of_experimental_colitis_/6232250
10.1371/journal.pone.0196994.g002