10.1371/journal.pone.0001424.g001
Morgane Rolland
Morgane
Rolland
David Heckerman
David
Heckerman
Wenjie Deng
Wenjie
Deng
Christine M. Rousseau
Christine
M. Rousseau
Hoosen Coovadia
Hoosen
Coovadia
Karen Bishop
Karen
Bishop
Philip J. R. Goulder
Philip
J. R. Goulder
Bruce D. Walker
Bruce
D. Walker
Christian Brander
Christian
Brander
James I. Mullins
James
I. Mullins
HIV-1 epitope repertoires and clinical data.
Public Library of Science
2013
epitope
repertoires
2013-02-21 11:17:40
Figure
https://plos.figshare.com/articles/figure/_HIV_1_epitope_repertoires_and_clinical_data_/610079
<p>Putative epitopes were identified <i>in silico</i> within full-length autologous HIV-1 proteomes and combined with previously described optimally defined CTL epitopes found in the LANL and IEDB databases. (A) and (B) respectively show the log viral loads and the CD4 counts plotted as a function of the number of predicted HIV-1 epitopes identified per proteome for the individuals with CD4 counts above 400 (n = 81). (C) Shows the number of predicted HIV-1 epitopes for individuals belonging to the highest (mean = 65) and lowest (mean = 76) viremia quartile. (D) Shows the average viral loads of individuals presenting a specific allele as a function of the average number of HIV-1 predicted epitopes for that allele (only alleles presented by at least 3 individuals in the South-African cohort were included).</p>