%0 Figure %A C. Stanley, Amanda %A Zhou, Yonghong %A H. Amante, Fiona %A M. Randall, Louise %A Haque, Ashraful %A G. Pellicci, Daniel %A R. Hill, Geoff %A Smyth, Mark J. %A I. Godfrey, Dale %A R. Engwerda, Christian %D 2008 %T Stimulation of iNKT Cells with α-GalCer during an Established Infection Exacerbates L. donovani Growth in the Liver. %U https://plos.figshare.com/articles/figure/_Stimulation_of_iNKT_Cells_with_GalCer_during_an_Established_Infection_Exacerbates_L_donovani_Growth_in_the_Liver_/606971 %R 10.1371/journal.ppat.1000028.g004 %2 https://plos.figshare.com/ndownloader/files/936535 %K inkt %K cells %K established %K exacerbates %X

C57BL/6 mice were infected with L. donovani and treated with either vehicle control (open bars) or 2 µg α-GalCer (closed bars) i.p., or injected i.v. with 5×105 vehicle-pulsed BMDC (open bars) or α-GalCer-pulsed BMDC (closed bars) on day 14 p.i.. Parasite burdens were determined in the liver at day 14 p.i. in untreated mice (grey bars; base-line parasite burden) and 1 wk later in treated groups, as indicated (A). Data represent the mean±SEM of parasite burdens (LDU) from four mice per group. Serum TNF (B) and IFNγ (C) levels at indicated time points are also shown. Statistical differences of p<0.05 (*) for vehicle versus α-GalCer treatment are indicated.

%I PLOS Pathogens