%0 Figure %A C. Stotz, Stephanie %A Vriens, Joris %A Martyn, Derek %A Clardy, Jon %A Clapham, David E. %D 2008 %T Citral inhibition of ITRPV1 reveals the expression of TRPV2 and TRPV3 in acutely isolated dorsal root ganglion neurons. %U https://plos.figshare.com/articles/figure/_Citral_inhibition_of_I_TRPV1_reveals_the_expression_of_TRPV2_and_TRPV3_in_acutely_isolated_dorsal_root_ganglion_neurons_/603024 %R 10.1371/journal.pone.0002082.g006 %2 https://plos.figshare.com/ndownloader/files/932588 %K inhibition %K reveals %K trpv2 %K trpv3 %K acutely %K dorsal %K ganglion %X

(A) Two patterns of response to repetitive 2-aminoethyldiphenyl borate application were noted within the dorsal root ganglion population following citral block of capsaicin-activated currents; dorsal root ganglion currents decreased in six neurons (left), and increased in the remaining neurons (right; n = 6; +100 mV). Holding potential = 0 mV. (B) Representative dorsal root ganglion currents from a neuron not potentiated by repeated 2-aminoethyldiphenyl borate application are shown. (C) Representative dorsal root ganglion currents from a neuron potentiated (2.3 fold; +100 mV) by repeated 2-aminoethyldiphenyl borate application are shown. (D) TRPV2 immunoreactivity in dorsal root ganglion neurons stained with 0.3 µg/ml anti-TRPV2 antibody+Alexa 488 secondary is shown (left; see Figure S5 for controls). Differential interference contrast image (right).

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